The Gotham S.T.A.R. Labs is a Gotham City branch of the international scientific research organization, S.T.A.R. Labs. This particular building, located in Gotham City's Otisburg district, contains transporter units used by STAR Labs personnel to teleport to various STAR Labs locations, including S.T.A.R. Labs Space Stations in orbit around the Earth.
Discovering that Brainiac was using a STAR Labs space station to store Exobyte data, Batman and the Joker send their forces to acquire the data and disrupt Brainiac's assimilation of the station. However, they soon discover that Brainiac was creating robotic duplicates of themselves and, upon discovery, sent the copies to destroy the original.