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Road to Hell is started once the player reaches level 21.
Speak with Blood Priest Lucius at the Burnley Night Club.
- "Circe's plans with the Cult of Blood are heating up. With Trigon's energy loose on this plan, we're in for a visit from an interdimensional force of evil...if you think you can handle it, talk to Blood Priest Lucius in Burnley for more." — Calculator
- Speak with Blood Priest Lucius in the Burnley Safehouse